Study Design Considerations in Veterinary Biologics
View Presentation *Brian J. Fergen, U.S. Department of Agriculture, Animal and Plant Health Inspection Service Keywords: Host animal efficacy studies are a natural situation for the consideration of the use of mixed models. Random effects associated with the design structure, which reflect the hierarchy associated with units of housing, animal sources, etc., are generally incorporated in the analysis of the study data from these studies. Recently, the use of generalized linear mixed models (GLMMs) has become more common as these models have the ability to model the design structure in a manner that reflects restrictions in the study randomization for non-normal data. In this presentation, we will identify key considerations in designing studies in Veterinary Biologics, with an emphasis on non-normal outcomes. These considerations include the statistic used to estimate efficacy, the multiple objectives associated with some studies, and a look at the appropriateness of the use of GLMMs for some study design and treatment structures.
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Key Dates
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April 30 - May 22, 2013
Invited Abstract Submission Open -
June 4, 2013
Online Registration Opens -
August 9 - August 23, 2013
Invited Abstract Editing -
August 23, 2013
Short Course materials due from Instructors -
August 26, 2013
Housing Deadline -
September 9, 2013
Cancellation Deadline and Registration Closes @ 11:59 pm EDT -
September 16 - September 18, 2013
Marriott Wardman Park, Washington, DC