Response Adaptive Randomization in Clinical Trials for Predictive Marker Validation
*Thomas E Gwise, FDA Keywords: predictive markers, adaptive designs Scientific advancement foreshadows the development of new predictive markers for use in selecting patient treatments. In this presentation, we will review several clinical trial designs suggested for validating such markers and discuss the potential for using response adaptive randomization in similar investigations. Results of simulation studies based on available clinical trial data will be presented to illustrate characteristics of the adaptive designs in this setting.
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Key Dates
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April 30 - May 22, 2013
Invited Abstract Submission Open -
June 4, 2013
Online Registration Opens -
August 9 - August 23, 2013
Invited Abstract Editing -
August 23, 2013
Short Course materials due from Instructors -
August 26, 2013
Housing Deadline -
September 9, 2013
Cancellation Deadline and Registration Closes @ 11:59 pm EDT -
September 16 - September 18, 2013
Marriott Wardman Park, Washington, DC