Sample size for equivalence trials: A case study from a vaccines lot consistency trial
View Presentation Alessandra Anemona, Novartis *Jitendra Ganju, Amgen Allen Izu, Novartis Keywords: sample size, power, equivalence trials For some trials simple but subtle assumptions can have a profound impact on the size of the trial. A case in point is a vaccine lot consistency (or equivalence) trial. Using published data we demonstrate that a slight, but realistic, change in how the sample size is calculated results in an increase in the sample size of nearly 300%.
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Key Dates
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April 30 - May 22, 2013
Invited Abstract Submission Open -
June 4, 2013
Online Registration Opens -
August 9 - August 23, 2013
Invited Abstract Editing -
August 23, 2013
Short Course materials due from Instructors -
August 26, 2013
Housing Deadline -
September 9, 2013
Cancellation Deadline and Registration Closes @ 11:59 pm EDT -
September 16 - September 18, 2013
Marriott Wardman Park, Washington, DC