Platform Trials: Statistical Efficiencies and Practical Examples
*Scott Berry, Berry Consultants 


Platform trials, in which multiple treatments, or multiple factorial treatments are explored in a single protocol create huge statistical efficiencies. These efficiencies include having increased power, for far smaller sample sizes relative to non-platform trials. The idea isn’t one of theoretical interest, in that there are many examples of emerging platform trials. These range from oncology, infectious disease, dementia, and even embedded trials within a learning healthcare system. In this talk I will outline some of the statistical efficiencies, common statistical aspects of platform trials, as well as providing some examples of platform trials from a wide range of therapeutic areas.