Getting the most from adaptive design: Pruning the Thorns
*Marc Walton, FDA CDER Keywords: adaptive design, efficiency Adaptive design clinical trials are recognized as more complex to plan and to conduct than simple fixed designs, but are widely thought to have the potential to significantly improve the efficiency and informativeness of drug development programs. This talk will identify a number of the issues that create difficulties in applying adaptive design to clinical trials in a drug development program, discuss why each is an important issue to be addressed, and some of the trade-offs that can be considered in doing so. In the final measure there are no universal solutions to gaining the full perceived potential from adaptive designs, and each drug development program will need to consider the specific features of each program.
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Key Dates
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November 1 - December 17, 2013
Online proposal submission for a session, short course and Town Hall Open -
January 6 - March 11, 2014
Online proposal submission for Roundtables Open -
April 30 - May 28, 2014
Abstract Submission Open -
June 4, 2014
Online Registration Opens -
August 8 - August 22, 2014
Invited Abstract Editing -
August 11, 2014
Short Course materials due from Instructors -
September 1, 2014
Housing Deadline -
September 15, 2014
Cancellation Deadline and Registration Closes @ 11:59 pm EDT -
September 22 - September 24, 2014
Marriott Wardman Park, Washington, DC