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Sex Disparities in Major Complications Following Partial Gastrectomy Among Gastric Cancer Patients: A Propensity Score-Matched Study Using ACS NSQIP Data (2015-2019) (305357)
Md Ashfaq Ahmed, Baptist Health South Florida
Peter McGranaghan, Baptist Health South Florida
Muni Rubens, Baptist Health South Florida
Anshul Saxena, Baptist Health South Florida
Emir Veledar, Baptist Health South Florida
*Zhenwei Zhang, Baptist Health South Florida
Keywords: bariatric surgery, gastric cancer, sex disparities
Post-op outcomes may differ between male and female gastric cancer (GC) patients who undergo partial gastrectomy (PG) due to underlying sex specific pathophysiology. In this study, we examined sex differences in major complications (MC) following PG. Adult GC patients from the ACS NSQIP registry, who underwent PG during 2015 - 2019 were included. The primary outcome was post-op MC. Propensity score matching (PSM) was done using: demographics, BMI, pre-op labs, & past medical history. Multivariate Logistic regression analysis was conducted. Overall 979 patients who underwent PG met our inclusion criteria and 762 were selected by PSM. After accounting for other variables Males had significantly higher odds of developing MC than females (AOR: 1.93; 95%CI: 1.10, 3.45). Our study found sex related disparities in MC even after PSM & it was higher among males. Healthcare providers should consider sex-specific management to improve post-gastrectomy recovery for men and reduce their excess burden.