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Divergent Nested Bar Plot for Binary Outcomes (305327)
*Weiming Du, Regeneron Pharmaceuticals
Rui Huang, Regeneron Pharmaceuticals
Toshio Kimura, Regeneron Pharmaceuticals
Brian Lin, Regeneron Pharmaceuticals
Keywords: Divergent, Nested Bar Plot, Binary Outcomes
Bar plots are commonly used in visualizing binary outcome. However, they are problematic when plotting multiple nested binary outcomes particularly when representing different directions of response (improvement vs worsening). One example in ophthalmology is the proportion improving or worsening at least 5, 10, or 15 ETDRS letters. In this scenario, outcomes are nested since patients with = 10-letter gain inherently has =5-letter gain. Existing solutions include: 1) plot multiple independent bar or nested bar plots, and 2) create stacked bar plots. Downsides of these solutions are losing the inherit nested relationship between outcomes and making the interpretation of the figure difficult. We propose a novel figure, the divergent nested bar plot, to solve this problem where two sets of nested bar plot are placed on opposing sides of the y-axis (positive: improvement; negative: worsening). This provides ease of comparison maintaining both the nested nature and the improvement/worsening relationship. This divergent nested bar plot is a marked improvement over existing solutions in visualizing multiple nested binary outcomes when they represent different directions of response.