Keywords: Safety, Bayesian
This presentation is from the ASA safety working group Bayesian methodology sub team. Bayesian approach for safety assessment incorporates prior knowledge about the safety profile of the treatments and updates knowledge based on accumulating data. The potential advantages of the Bayesian approach relative to classical frequentist statistical methods include the flexibility of incorporating the current knowledge of the safety profile originating from multiple sources into the decision-making process. In this presentation, different prior approach will be compared for the application of safety assessment of adverse events.