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All Times EDT

Friday, September 24
Fri, Sep 24, 3:45 PM - 5:00 PM
Virtual
Digital Data, Endpoints, and Analyses: Regulatory Guidance for Clinical Trials

Functional Data Methods for Intensely Longitudinal Wearable Device Data (303515)

*Jeff Goldsmith, Columbia University 

Keywords: Big data, smoothing, regression, dimension reduction

In the last ten years, technological advances have made many activity- and physiology-monitoring wearable devices available for use in large-scale clinical and epidemiological studies. This trend is likely to continue and even expand as devices become cheaper and more reliable. These developments open up a tremendous opportunity for clinical and public health researchers to collect critical data at an unprecedented level of detail, while posing new challenges for statistical analysis of rich, complex data. This talk will present a collection of approaches in functional data analysis for identifying and interpreting variability in activity trajectories within and across participants, for building regression models in which activity trajectories are the response, and for understanding shifts in the circadian rhythms that underly the timing of activity.