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CC = Walter E. Washington Convention Center M = Marriott Marquis Washington, DC
* = applied session ! = JSM meeting theme
Activity Details
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323 * !
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Tue, 8/9/2022,
2:00 PM -
3:50 PM
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CC-201
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Adaptive Enrichment Designs in Clinical Trials — Topic Contributed Papers
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Biopharmaceutical Section, Biometrics Section, ENAR
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Organizer(s): Daniel Zhao, University of Oklahoma
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Chair(s): Daniel Zhao, University of Oklahoma
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2:05 PM
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Adaptive Designs with Modified Testing Hierarchy at the Interim
George Kordzakhia, Astra Zeneca; Cassie Dong, Takeda ; Eiji Ishida, Sunovion
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2:25 PM
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A Bayesian Group Sequential Enrichment Design with Adaptive Regression of Response and Survival Time on Baseline Biomarkers
Peter Thall, The University of Texas MD Anderson Cancer Center; Yeonhee Park, University of Wisconsin-Madison; Suyu Liu, The University of Texas MD Anderson Cancer Center; Ying Yuan , the University of Texas MD Anderson Cancer Center
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2:45 PM
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Overview of Existing Methods for Biomarker-Driven Adaptive Designs
Ilya Lipkovich, Eli Lilly and Company; Sarah Johnston, Bristol-Myers Squibb; Alex Dmitrienko, Mediana, Inc; Daniel Zhao, University of Oklahoma
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3:05 PM
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Decision Theoretic Approaches for the Design of Adaptive Enrichment and Umbrella Trials
Martin Posch, Medical University of Vienna
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3:25 PM
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Discussant: Brian Wiens, ACELYRIN, INC.
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3:45 PM
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Floor Discussion
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Video Available to all JSM Registered Attendees. Please login to view.
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