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579 * ! Thu, 8/6/2020, 3:00 PM - 4:50 PM Virtual
30 Years Journey of Bayesian Adaptive Designs: From Bayesian Monitoring to Dynamic Treatment Regime — in Honor of Dr. Peter Thall’s 70th Birthday — Topic Contributed Papers
Biopharmaceutical Section, WNAR, Biometrics Section
Organizer(s): Ruitao LIN, The University of Texas MD Anderson Cancer Center
Chair(s): Ying Yuan, The University of Texas MD Anderson Cancer Center
3:05 PM Subgroup-Specific Dose Finding in Phase I Clinical Trials Based on Time to Toxicity Allowing Adaptive Subgroup Combination
Andrew Genius Chapple, LSUHSC; Peter F. Thall, M.D. Anderson Cancer Center
3:25 PM An Adaptive Trial Design to Optimize Dose Schedule Regimes with Delayed Outcomes
Ruitao LIN, The University of Texas MD Anderson Cancer Center; Ying Yuan, The University of Texas MD Anderson Cancer Center; Peter F. Thall, M.D. Anderson Cancer Center
3:45 PM Robust Adaptive Incorporation of Historical Control Data in a Randomized Trial of External Cooling to Treat Septic Shock
Thomas Murray, University of Minnesota; Peter F. Thall, M.D. Anderson Cancer Center; Frederique ARTHUR Schortgen, Groupe Hospitalier Henri-Mondor; Sarah ARTHUR Zohar, Centre de Recherche des Cordeliers; Sandrine Katsahian, Hopital Europen Georges-Pompidou
4:05 PM Rethinking Prior Effective Sample Size
Satoshi Morita, Kyoto University
4:25 PM Utilizing Bayesian Analysis for Probabilistic Decision Making in a Platform Clinical Trial
J. Wathen, Gilead Sciences
4:45 PM Floor Discussion