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Legend:
CC = Vancouver Convention Centre   F = Fairmont Waterfront Vancouver
* = applied session       ! = JSM meeting theme

Activity Details


12 * !
Sun, 7/29/2018, 2:00 PM - 3:50 PM CC-West 224
Novel Statistical Methods for Analyzing Electronic Health Records and Biobank Data — Invited Papers
WNAR, International Chinese Statistical Association, ENAR
Organizer(s): Ran Tao, Vanderbilt University Medical Center
Chair(s): Ran Tao, Vanderbilt University Medical Center
2:05 PM Retrospective Study Designs for Longitudinal Data Obtained from a Biobank-Linked Electronic Medical Record
Presentation
Jonathan Schildcrout, Vanderbilt University Medical Center
2:30 PM Efficiently Controlling for Unbalanced Case-Control Ratios and Sample Relatedness for Binary Traits in PheWAS by Large Cohorts
Presentation
Seunggeun Lee, University of Michigan
2:55 PM Scalable Methods for Association Analysis in Biobank Scale Data Sets
Presentation
Dajiang Liu, Penn State College of Medicine
3:20 PM Enabling Phenotypic Big Data with PheNorm
Presentation
Sheng Yu, Tsinghua University; Yumeng Ma, Tsinghua University; Jessica Gronsbell, Harvard T.H. Chan School of Public Health; Tianrun Cai, Brigham and Women's Hospital; Ashwin Ananthakrishnan, Massachusetts General Hospital; Vivian Gainer, Partners HealthCare; Susanne Churchill, Harvard Medical School; Peter Szolovits, Massachusetts Institute of Technology; Shawn Murphy, Partners HealthCare; Isaac Kohane, Harvard Medical School; Katherine Liao, Brigham and Women's Hospital; Tianxi Cai, Harvard T.H. Chan School of Public Health
3:45 PM Floor Discussion
 
 

13 *
Sun, 7/29/2018, 2:00 PM - 3:50 PM CC-West 222
Integrative Approaches for Analysis of Complex Phenotype and DNA Sequence Data — Invited Papers
ENAR, WNAR, Section on Statistics in Genomics and Genetics
Organizer(s): Dmitri Zaykin, National Institute of Environmental Health Sciences
Chair(s): Dmitri Zaykin, National Institute of Environmental Health Sciences
2:05 PM Simultaneous Genetic Analysis of Sequence Data from a Pair of Organisms That Jointly Influence a Phenotype
Mary Sara McPeek, University of Chicago; Miaoyan Wang, UC Berkeley
2:25 PM Genetic Analysis of High-Dimensional Phenotypes
Presentation
Michael Philip Epstein, Emory University
2:45 PM Rare Variant Prioritization Using Structure-Supervised Locus-Specific Tests
Presentation
Jung-Ying Tzeng, North Carolina State University; Rachel Marceau, North Carolina State University; Wenbin Lu, North Carolina State University
3:05 PM Unified Sequence Based Association Tests Allowing for Multiple Functional Annotation Scores, and Applications to Meta-Analysis of Noncoding Variation in Metabochip Data
Iuliana Ionita-Laza, Columbia University
3:25 PM Discussant: Olga Vsevolozhskaya, University of Kentucky
3:45 PM Floor Discussion
 
 

87
Sun, 7/29/2018, 8:30 PM - 10:30 PM CC-West Hall B
Invited ePoster Session: a Statistical Smörgåsbord — Invited Poster Presentations
SSC, Section on Bayesian Statistical Science, Section on Statistics in Epidemiology, Section on Statistical Learning and Data Science, Section on Nonparametric Statistics, Biometrics Section, Section on Statistics and the Environment, Section for Statistical Programmers and Analysts, Section on Statistics in Imaging, WNAR, Social Statistics Section, Astrostatistics Special Interest Group, Biopharmaceutical Section, ENAR, Section on Risk Analysis, Section on Statistical Consulting
Chair(s): Paul McNicholas, McMaster University
1: The LISA 2020 Program to Build Statistics Capacity in Developing Countries
Eric Vance, LISA-University of Colorado Boulder
2: Conditions for the Uniqueness, Finiteness, and Possible Location of the Maximum Likelihood Estimate with a Log Binomial Model
Gurbakhshash Singh, University of Calgary; Gordon Hilton Fick, University of Calgary
3: Two Mixture-Based Clustering Approaches: Modeling an Automobile Insurance Portfolio
Tatjana Miljkovic, Miami University; Daniel Fernandez, Victoria University of Wellington
4: An Expectation Conditional Maximization Approach for Gaussian Graphical Models
Zehang Li, University of Washington; Tyler McCormick, University of Washington
5: A Bayesian Model for Multivariate Micro-Level Insurance Claims
Marie-Pier Côté, Universite Laval; Christian Genest, McGill University; David A Stephens, McGill University
6: Deep Learning for Statistical Inference in Infectious Disease Systems
Rob Deardon, University of Calgary; Carolyn Augusta, University of Guelph; Graham Taylor, University of Guelph
7: Flexible Accelerated Failure Time Model in Survival Analysis
Menglan Pang, McGill University; Michal Abrahamowicz, McGill University; Robert W Platt, McGill University
8: Spatio-Temporal Analysis of Children and Adolescents' Emergency Department Use for Mental Health Reasons in Alberta, Canada
Michelle Thiessen, Simon Fraser University; Joan Hu, Simon Fraser University; Rhonda J. Rosychuk, University of Alberta
9: Approximate Bayesian Computation with Complex High-Dimensional Data and Limited Simulations
Taylor Gene Pospisil, Carnegie Mellon University
10: Zero Counts in Single Cell RNA-Seq Data
Hao Wu, Emory University; Zhijin Wu, Brown University
11: Quasi-Oracle Estimation of Heterogeneous Treatment Effects
Xinkun Nie, Stanford University; Stefan Wager, Stanford University
12: Estimation of Fire Duration Distribution with Missing Start Time
Yi Xiong, Simon Fraser University; John Braun, University of British Columbia ; Joan Hu, Simon Fraser University
13: Bayesian Nonparametric Hierarchical Models for Lightcurve Classification and Observation Decisions
David Edward Jones, Duke University and SAMSI; Sujit Ghosh, North Carolina State Univ.; Ana-Maria Staicu, NC State University; Ashish Mahabal, Caltech
14: Approximate Bayesian Computation for the Stellar Initial Mass Function
Jessi Cisewski-Kehe, Yale University; Chad Schafer, Carnegie Mellon University; Grant Weller, Savvysherpa; David Hogg, New York University
15: A Novel Bayesian Framework to Probe Closed Box Nature of Galaxy Clusters
Arya Farahi, University of Michigan - Ann Arbor
16: Statistical Approaches to Decreasing the Discrepancy of Non-Detects in QPCR Data
Valeriia Sherina, University of Rochester Medical Center; Love Tanzy, University of Rochester Medical Center; Matthew N. McCall, University of Rochester Medical Center
17: Generalized Statistical Inference for Astrophysical Discoveries
Sara Algeri, Imperial College London; David A van Dyk, Imperial College London; Jan Conrad, Oskar Klein Centre for Cosmoparticle Physics
18: Nonparametric Causal Effects Based on Incremental Propensity Score Interventions
Edward Kennedy, Carnegie Mellon University; Matteo Bonvini, Carnegie Mellon University
19: Addressing Overfitting in Mixtures of Factor Analyzers
Jeffrey L Andrews, University of British Columbia Okanagan
20: Spatiotemporal Analysis of Environmental Health Risk
Renjun Ma, University of New Brunswick; Edward Hughes, Edward Hughes Consulting
21: Probabilistic Partial Least Squares Regression Applied to Longitudinal and Cross-Sectional Compositional Data
Peter A Tait, McMaster Univeristy; Paul McNicholas, McMaster University
22: Detection of Trend Onset in Environmental Time Series
Ying Zhang, Acadia University
23: The Analysis of Face Perception MEG and EEG Data Using a Potts-Mixture Spatiotemporal Joint Model
Yin Song, University of Victoria; Farouk Nathoo; Arif Babul, University of Victoria
24: Infere
Steven Cumming, Université Laval
25: Functional Partial Linear Quantile Regression Based on Reproducing Kernel Hilbert Space
Peng Liu, University of Alberta; Linglong KONG, University of Alberta; Bei JIANG, University of Alberta; Nan Zhang, Fudan University; Jianhua Z. Huang, Texas A&M University
26: Gaussian Process Regression with Large Data Sets: Has the Problem Been Solved?
Sonja Surjanovic, University of British Columbia; William Welch, University of British Columbia
27: Sparse Estimation for Functional Semiparametric Additive Model
Peijun Sang, Simon Fraser University; Richard Lockhart, Simon Fraser University; Jiguo Cao, Simon Fraser University
28: Analysis of Paired Binary Data Subject to Misclassification Using a Random Effect Model
Hua Shen, University of Calgary ; Richard John Cook, University of Waterloo
29: A Grouped Weighted Quantile Regression Approach to Modeling Environmental Chemical Mixtures and Childhood Leukemia Risk
David C. Wheeler, Virginia Commonwealth University
30: Efficient Robust Doubly Adaptive Regularized Regression with Application to fMRI Data
Wei Tu, University of Alberta
31: A Model-Based Clustering to Identify Disease-Associated SNPs
Li Xing, University of Victoria; Xuekui Zhang, University of Victoria; Yan Xu, University of Victoria; Weiliang Qiu, Brigham and Women's Hosptial/Harvard Medical School
32: The Consequences of Requiring 'Greater Statistical Stringency' for Scientific Publication
Harlan Campbell, University of British Columbia; Paul Gustafson, University of British Columbia
33: Mixtures of Contaminated Shifted Asymmetric Laplace Factor Analyzers
Brian C Franczak, MacEwan University
34: Uncertainty Quantification of Stochastic Computer Model for Binary Black Hole Formation
Luyao Lin, Simon Fraser University; Jim Barrett, University of Birmingham; Derek Bingham, Simon Fraser University; Ilya Mandel, University of Birmingham
35: Network Meta-Analysis of Disconnected Networks: How Dangerous Are Random Baseline Treatment Effects?
Audrey Béliveau, University of Waterloo; Sarah Goring, SMG Outcomes Research; Robert W Platt, McGill University; Paul Gustafson, University of British Columbia
36: Nonparametric Measures of Local Causality and Tests of Local Non-Causality in Time Series
Felix Camirand Lemyre, School of mathematics and statistics, University of Melbourne; Taoufik Bouezmarni, Université de Sherbrooke; Jean-François Quessy, Université du Québec à Trois-Rivières
37: Sparse Functional Principal Component Analysis in a New Regression Framework
YUNLONG NIE, Simon Fraser University; Jiguo Cao, Simon Fraser University
38: Inference of Introgressive Hybridization in Anopheles Mosquito Genomes
Jingxue(Grace) Feng, Simon Fraser University; Liangliang Wang, Simon Fraser University; Cedric Chauve, Simon Fraser University
39: Statistical Methods for Addressing Missing Data in HIV/AIDS Surveillance Systems
Sahar Zangeneh, Fred Hutchinson Cancer Research Center; Ying Qing Chen, Fred Hutchinson Cancer Research Center; Deborah Donnell, Fred Hutch
40: Latent Mixtures of Functions to Characterize the Complex Exposure Relationships of Pesticides on Cancer Incidence
Sung Duk Kim, National Cancer Institute; Paul S Albert, National Cancer Institute
 
 

142 * !
Mon, 7/30/2018, 10:30 AM - 12:20 PM CC-West 217
Metabolomics Data Analytics - the New Frontier in Precision Medicine — Invited Papers
WNAR, Section on Statistics in Genomics and Genetics, ENAR, SSC
Organizer(s): Katerina Kechris, Colorado School of Public Health; Jean Yee Hwa Yang, University of Sydney, Australia
Chair(s): Jean Yee Hwa Yang, University of Sydney, Australia
10:35 AM Hierarchical Processing for LC/MS Metabolomics Data Generated in Multiple Batches
Douglas Walker, Emory University; Karan Uppal, Emory University; Dean Jones, Emory University; Tianwei Yu, Emory University
11:25 AM Bayesian Network Models for Integrating Genetics and Metabolomics Data
Presentation
Denise Marie Scholtens, Northwestern University; Alan Kuang, Northwestern University
11:50 AM Discussant: Susmita Datta, University of Florida
12:15 PM Floor Discussion
 
 

217 *
Mon, 7/30/2018, 2:00 PM - 3:50 PM CC-East 16
Studying Psychiatric Disorders Using Statistical and Machine Learning Methods — Invited Papers
Mental Health Statistics Section, ENAR, WNAR, SSC
Organizer(s): Hongyuan Cao, University of Missouri-Columbia
Chair(s): Lei Liu, Washington University in St Louis
2:05 PM SAME-Clustering: Single-Cell Aggregated Clustering via Mixture Model Ensemble
Presentation 1 Presentation 2
Ruth Huh, University of North Carolina at Chapel Hill; Yuchen Yang, University of North Carolina at Chapel Hill; Houston Culpepper, University of North Carolina at Chapel Hill; Yun Li, University of North Carolina at Chapel Hill
2:30 PM Statistical Methods for Integrative Analysis of Multi-Omics Data with Applications to Psychiatric Disorders
Hongyuan Cao, University of Missouri-Columbia; Jun Chen, Mayo Clinic; Xianyang Zhang, Texas A&M University
2:55 PM Statistical Challenges and Opportunities for Analysis of Massive Biobank Data
Presentation
Xihong Lin, Harvard University
3:20 PM Analysis of Mental Disorder Omics Data: An Integrative Perspective
Shuangge Ma, Yale University
3:45 PM Floor Discussion
 
 

227 * !
Mon, 7/30/2018, 2:00 PM - 3:50 PM CC-West 203
Bayesian Variable Selection and Shrinkage in Epidemiology Studies — Topic Contributed Papers
Section on Statistics in Epidemiology, International Indian Statistical Association, WNAR
Organizer(s): Jaya M Satagopan, Memorial Sloan Kettering Cancer Center
Chair(s): Sujata M Patil, Memorial Sloan Kettering Cancer Center
2:05 PM A Bayesian Hierarchical Framework for Pathway Analysis in Genome-Wide Association Studies
Swati Biswas, University of Texas at Dallas; Lei Zhang, University of Texas at Dallas; Pankaj Choudhary, University of Texas at Dallas
2:25 PM A Default Prior for the Intercept Parameter in Logistic Regression
Presentation
Philip Boonstra, University of Michigan; Ananda Sen, University of Michigan
2:45 PM Dynamic Variable Selection with Spike-And-Slab Process Priors
Presentation
Kenichiro McAlinn, University of Chicago; Veronika Rockova, University of Chicago
3:05 PM Multiethnic Joint Analysis of Marginal SNP Effects
Presentation
David Conti, University of Southern California; Kan Wang, University of Southern California; Chris Haiman, University of Southern California; Paul Newcombe, MRC Biostatistics Unit
3:25 PM Penalized Shrinkage Estimation in Reduced-Rank Time-To-Event Data
Presentation
Ananda Sen, University of Michigan
3:45 PM Floor Discussion
 
 

272 !
Tue, 7/31/2018, 8:30 AM - 10:20 AM CC-West 214
Advances in Statistical Methods for Meta?Analysis — Invited Papers
General Methodology, WNAR
Organizer(s): Ludovic Trinquart, Boston University School of Public Health
Chair(s): Michael LaValley, Boston University School of Public Health
8:35 AM A Re-Evaluation of Fixed Effect(s) Meta-Analysis
Presentation
Kenneth Rice, University of Washington; Julian Higgins, University of Bristol; Thomas Lumley, University of Auckland
8:55 AM The Myth of Making Inference for Overall Treatment Efficacy with Data from Multiple Studies via Meta-Analysis
Presentation
Brian Claggett, Harvard Medical School
9:15 AM Imputation Methods for Individual Participant Data Meta-Analysis
Presentation
Eloise Kaizar, Ohio State University; Deborah Kunkel, The Ohio State University
9:35 AM Multivariate Meta-Analysis Model for the Difference in Restricted Mean Survival Times
Isabelle R Weir, Boston University School of Public Health; Ludovic Trinquart, Boston University School of Public Health
9:55 AM Multivariate Network Meta-Analysis to Mitigate Outcome Reporting Bias
Stacia Marie DeSantis, University of Texas Health Science Center at Houston
10:15 AM Floor Discussion
 
 

276 *
Tue, 7/31/2018, 8:30 AM - 10:20 AM CC-West 222
Addressing Emerging Statistical Challenges in Microbiome Studies — Invited Papers
WNAR, ENAR, Section on Statistics in Genomics and Genetics
Organizer(s): Michael C. Wu, Fred Hutchinson Cancer Research Center
Chair(s): Michael C. Wu, Fred Hutchinson Cancer Research Center
8:35 AM A Framework for Multivariate Causal Mediation Analysis with Microbiome Data
Alexander V Alekseyenko, Medical University of South Carolina
9:05 AM Analyzing Matched Sets of Microbiome Data Using the Linear Decomposition Model
Presentation
Glen Alan Satten, Centers for Disease Control and Prevention; Yijuan Hu, Emory University; Zhengyi Zhu, Emory University
9:35 AM Trend Tests for Microbiome Data
Abhishek Kaul, WSU; Shyamal Peddada, Univeristy of Pittsburgh; Siddhartha Mandal, Public Health Foundation of India; Ori Davidov , Haifa Univeristy
10:05 AM Floor Discussion
 
 

277 !
Tue, 7/31/2018, 8:30 AM - 10:20 AM CC-West 224
Recent Advances in Methods to Address Measurement Error — Invited Papers
Biometrics Section, ENAR, WNAR
Organizer(s): Pamela A Shaw, University of Pennsylvania
Chair(s): Sharon X Xie, University of Pennsylvania
8:35 AM Correcting for Errors in Variables Derived from Electronic Health Records Using Validation Sampling and Multiple Imputation
Bryan E Shepherd, Vanderbilt University School of Medicine; Mark Giganti, Vanderbilt University School of Medicine
9:00 AM On the Use of Raking to Improve Regression Calibration: A Flexible Method to Address Error-Induced Bias Efficiently
Eric Oh, University of Pennsylvania; Pamela A Shaw, University of Pennsylvania
9:25 AM Big Data as a Measurement Error Problem
Presentation
Raymond J. Carroll, Texas A & M University; Ya Su, Texas A&M University; Anirban Bhattacharya, Texas A&M University; Yan Zhang, Johns Hopkins University; Nilanjan Chatterjee, Johns Hopkins University
9:50 AM Recent Developments in Modeling Nonlinear Relationships in the Presence of Measurement Error
Presentation
Ruth Keogh, London School of Hygiene & Tropical Medicine; Christen Gray, London School of Hygiene & Tropical Medicine
10:15 AM Floor Discussion
 
 

318 * !
Tue, 7/31/2018, 10:30 AM - 12:20 PM CC-West 211
Advances on the Analysis of Single-Cell Sequencing Data — Invited Papers
WNAR, Section on Statistics in Genomics and Genetics, International Chinese Statistical Association, SSC
Organizer(s): Lingling An, University of Arizona
Chair(s): Lingling An, University of Arizona
10:35 AM Statistical Methods for Single-Cell RNA-Seq in Studies of Mammalian Development
Christina Kendziorski, University of Wisconsin - Madison; Zijian Wang, University of Wisconsin - Madison; Ron Stewart, Morgridge Institute for Research; Chris Barry, Morgridge Institute for Research; Li-Fang Chu, Morgridge Institute for Research
11:00 AM General and Flexible Methods for Signal Extraction from Single-Cell RNA-Seq Data
Presentation
Davide Risso, Weill Cornell Medicine
11:25 AM Multi-Sample Differential Expression Analysis of RNA-Seq Single-Cell Data
George Tseng, University of Pittsburgh; Li Zhu, University of Pittsburgh; An-Shun Tai, National Tsing Hua University; Wei Chen, University of Pittsburgh
11:50 AM Modeling Allele-Specific Gene Expression by Single-Cell RNA Sequencing
Presentation
Yuchao Jiang, University of North Carolina, Chapel Hill; Nancy Zhang, University of Pennsylvania; Mingyao Li, University of Pennsylvania
12:15 PM Floor Discussion
 
 

321 *
Tue, 7/31/2018, 10:30 AM - 12:20 PM CC-West 306
Detecting Structural Change in Complex Data — Invited Papers
International Chinese Statistical Association, WNAR, IMS
Organizer(s): Ning Hao, University of Arizona
Chair(s): Yue S Niu, University of Arizona
10:35 AM The Screening and Ranking Algorithm for Change-Points Detection in Multiple Samples
Presentation
Heping Zhang, Yale University School of Public Health
11:00 AM Penalized Versus Segmentation Methods in Changepoint Problems
Presentation
Ryan Tibshirani, Carnegie Mellon University; Sangwon Hyun, Carnegie Mellon University; Kevin Lin, Carnegie Mellon University; Max G'Sell, Carnegie Mellon University
11:25 AM Nonparametric Independence Testing via Mutual Information
Presentation
Thomas B. Berrett, University of Cambridge; Richard J Samworth, University of Cambridge
11:50 AM A New Class of Change Point Test Statistics of Renyi Type
Presentation
Gregory Rice, University of Waterloo; Lajos Horvath, University of Utah
12:15 PM Floor Discussion
 
 

361
Tue, 7/31/2018, 10:30 AM - 12:20 PM CC-West Hall B
Contributed Poster Presentations: WNAR — Contributed Poster Presentations
WNAR
Chair(s): Paul McNicholas, McMaster University
71: Generating Survival Times Using Cox Proportional Hazards Models with Cyclic Time-Varying Covariates
Yunda Huang, Fred Hutchinson Cancer Research Center; Lily Zhang, Fred Hutchinson Cancer Research Center; Zong Zhang, Interlake High School; Peter Gilbert, Fred Hutchinson Cancer Research Center
72: A Bayesian Model for Repeated Measures Count Data with Multiple Inflated Values
Benjamin Rogers, UCLA
 
 

385 * !
Tue, 7/31/2018, 2:00 PM - 3:50 PM CC-West 110
Appropriate Estimators for Various Clinical Trial Estimands: Are We There Yet? — Invited Papers
Biopharmaceutical Section, ENAR, WNAR
Organizer(s): Pilar Lim, PhD, Janssen Research & Development, LLC
Chair(s): Yun Zhang, Janssen Research & Development, LLC
2:05 PM What Do We Know About Estimators for the Treatment Policy Estimand?
Presentation
Elena Polverejan, Janssen R&D; Vladimir Dragalin, Janssen R&D
2:30 PM Performance of Pattern Mixture Model Estimators with and Without Patient-Level Imputation
Presentation
Bohdana Ratitch, IQVIA; Ilya Lipkovich, IQVIA; Michael O'Kelly, IQVIA
2:55 PM Undiluting the Treatment Effect
Presentation
Thomas Permutt, Food and Drug Administration
3:20 PM Discussant: Craig Mallinckrodt, PhD, Eli Lilly and Company
3:45 PM Floor Discussion
 
 

386 * !
Tue, 7/31/2018, 2:00 PM - 3:50 PM CC-West 119
Recent Developments in Integrating Multiple-Omics Data in Complex Diseases — Invited Papers
ENAR, International Chinese Statistical Association, WNAR, SSC
Organizer(s): Li Hsu, Fred Hutchinson Cancer Research Center, USA; Yu-Ru Su, Fred Hutchinson Cancer Research Center
Chair(s): Yu-Ru Su, Fred Hutchinson Cancer Research Center
2:05 PM Constructing Tumor-Specific Gene Regulatory Networks Based on Sample with Tumor Purity Heterogeneity
Pei Wang, Icahn School of Medicine at Mount Sinai ; Francesca Petralia, Icahn School of Medicine at Mount Sinai; Li Wang, Icahn School of Medicine at Mount Sinai; Jie Peng, UC Davis
2:25 PM A Multivariate Mixed-Effects Selection Model Framework for Batch-Processed Proteomics Data with Nonignorable Missingness
Presentation
Jiebiao Wang, Carnegie Mellon University; Pei Wang, Icahn School of Medicine at Mount Sinai ; Donald Hedeker, University of Chicago; Lin Chen, University of Chicago
2:45 PM Variation and Genetic Control of Protein Abundance in Human Tissues
Presentation
Hua Tang, Stanford Dept. of Genetics
3:05 PM A General Framework for Integrating GWAS Data with Molecular Endophenotypes
Presentation
Wei Pan, University of Minnesota
3:25 PM A Versatile and Adaptive Multiple Functional Annotations-Based Association Test of Whole-Genome Sequencing Data
Presentation
Peng Wei, The University of Texas MD Anderson Cancer Center; Yiding Ma, The University of Texas MD Anderson Cancer Center
3:45 PM Floor Discussion
 
 

454 * !
Wed, 8/1/2018, 8:30 AM - 10:20 AM CC-West 110
Advances and Applications of Joint Modeling for Longitudinal and Time-To-Event Data — Invited Papers
WNAR, ENAR, Biometrics Section, SSC
Organizer(s): Peter Gilbert, Fred Hutchinson Cancer Research Center; Yunda Huang, Fred Hutchinson Cancer Research Center
Chair(s): Ross Prentice, Fred Hutchinson Cancer Research Center
8:35 AM A Nonlinear Model for Truncated and Mismeasured Time-Varying Covariates in Joint Models for Longitudinal and Survival Data
Presentation
Lang Wu, University of British Columbia
8:55 AM Joint Analysis of Multiple Highly Correlated Biomarkers and an Event Time via a Longitudinal Principal Component Approach
Gang Li, UCLA
9:15 AM Improve Risk Prediction Model Estimation with Longitudinal Surrogate Markers
Presentation
Yu Zheng, Harvard T.H. Chan School of Public Health; Tianxi Cai, Harvard T.H. Chan School of Public Health; Lu Tian, Stanford University School of Medicine
9:35 AM Assessing Pharmacokinetic Marker Correlates of a Failure Time Outcome, with Application to HIV Prevention Efficacy Trials
Presentation
Peter Gilbert, Fred Hutchinson Cancer Research Center; Lily Zhang, Fred Hutchinson Cancer Research Center; Erika Thommes, Fred Hutchinson Cancer Research Center; Yunda Huang, Fred Hutchinson Cancer Research Center
9:55 AM Discussant: Patrick James Heagerty, University of Washington
10:15 AM Floor Discussion
 
 

467 *
Wed, 8/1/2018, 8:30 AM - 10:20 AM CC-West 122
Statistical Advances for Cancer Genomics and Immunogenomics - from Single-Cell to Correlated Population — Topic Contributed Papers
Biometrics Section, Section on Statistics in Genomics and Genetics, WNAR, SSC
Organizer(s): Qunhua Li, Penn State University
Chair(s): Ying Huang, Fred Hutchinson Cancer Research Center
8:35 AM Variability-Preserving Imputation for Accurate Gene Expression Recovery in Single Cell RNA Sequencing Studies
Presentation
Mengjie Chen, University of Chicago; Xiang Zhou, U of Michigan
8:55 AM ScImpute: Accurate and Robust Imputation for Single Cell RNA-Seq Data
Presentation
Jingyi Li, University of California, Los Angeles; Wei Li, University of California, Los Angeles
9:15 AM Using RNA-Seq Data to Study Patients' Response on Tumor Immunotherapy
Wei Sun, Fred Hutchinson Cancer Research Center; Chong Jin, UNC-Chapel Hill; Paul Little, UNC Chapel Hill; Danyu Lin, University of North Carolina; Mengjie Chen, University of Chicago
9:35 AM A Discrete Threshold Model for the Clone Size Distribution of the Immune Repertoire
Qunhua Li, Penn State University; Hillary Koch, Penn State University; Dmytro Starenki, Hudson Alpha Institute for Biotechnology; Sara Cooper, HudsonAlpha Institute of Biotechnology; Rick Myers, HudsonAlpha Institute of Biotechnology
9:55 AM Sequencing Data, Repeated Measures and Genetic Heritability
Katerina Kechris, Colorado School of Public Health; Brian Vestal, National Jewish Health; Wen Jenny Shi, University of Colorado Anschutz Medical Campus; Pratyaydipta Rudra, University of Colorado at Denver; Pamela Russell, University of Colorado Anschutz Medical Campus; Laura Saba, University of Colorado Anschutz Medical Campus
10:15 AM Floor Discussion
 
 

569 * !
Wed, 8/1/2018, 2:00 PM - 3:50 PM CC-West 121
Theory and Practice for Addressing Asymmetric Measures in Statistical Modeling — Topic Contributed Papers
WNAR, Biometrics Section, International Chinese Statistical Association
Organizer(s): Ying Lu, Stanford University; Milan Stehlik, Johannes Kepler University and University of Valparaiso
Chair(s): Lu Tian, Stanford University School of Medicine
2:05 PM On Modeling of Asymmetric Dependencies
Milan Stehlik, Johannes Kepler University and University of Valparaiso
2:25 PM Dependencies in Binary Regression Data Generated by Informed Sequential Dose Allocation
Presentation
Nancy Flournoy, University of Missouri; Assaf Oron, Instutue for Disease Modeling
2:45 PM Model Selection Criteria Based on Symmetrized Variants of Asymmetric Divergence Measures
Joseph Cavanaugh, University of Iowa
3:05 PM Discussant: Ying Lu, Stanford University
3:25 PM Floor Discussion
 
 

602
Thu, 8/2/2018, 8:30 AM - 10:20 AM CC-West 222
Theory at the Intersection of Machine Learning and Statistics — Invited Papers
IMS, Mathematical Association of America, WNAR, SSC
Organizer(s): Andrew B Nobel, University of North Carolina at Chapel Hill
Chair(s): Andrew B Nobel, University of North Carolina at Chapel Hill
8:35 AM Sequential Prediction, Martingale Tail Bounds and Automatic Machine Learning
Karthik Sridharan, Cornell University
9:00 AM Inference for Recursive Trees
Presentation
Nicolas Fraiman, University of North Carolina at Chapel Hill; Shankar Bhamidi, University of North Carolina at Chapel Hill; Andrew B Nobel, University of North Carolina at Chapel Hill; Ruituo Fan, University of North Carolina at Chapel Hill
9:25 AM Statistical Properties of Deep Networks
Presentation
Peter Bartlett, UC Berkeley
9:50 AM Subsampling and Symmetry in Networks
Presentation
Peter Orbanz, Columbia University
10:15 AM Floor Discussion
 
 

643
Thu, 8/2/2018, 10:30 AM - 12:20 PM CC-West 117
Biomarkers and Clinical Trials — Invited Papers
WNAR, Biopharmaceutical Section, Society for Clinical Trials, SSC
Organizer(s): Kathleen F. Kerr, University of Washington
Chair(s): Yingqi Zhao, Fred Hutchinson Cancer Research Center
10:35 AM Evaluating Biomarkers for Prognostic Enrichment of Clinical Trials
Kathleen F. Kerr, University of Washington; Jeremy Roth, University of Washington; Kehao Zhu, Axio Research; Heather Thiessen-Philbrook, Yale University; Allison Meisner, Johns Hopkins University; Francis Perry Wilson, Yale University; Steven Coca, Icahn School of Medicine at Mount Sinai; Chirag Parikh, Yale University
11:00 AM Using Surrogate Biomarker Information to Plan a Future Clinical Trial
Presentation
Layla Parast, RAND; Tianxi Cai, Harvard T.H. Chan School of Public Health; Lu Tian, Stanford University School of Medicine
11:25 AM Biomarker Guided Phase II Two-Stage Design for Targeted Therapy
Zheyu Wang, Johns Hopkins University; Fujun Wang, Medimmune; Chenguang Wang, Johns Hopkins University; Gary Rosner, Johns Hopkins University; Jianliang Zhang, Medimmune; Hao Wang, Johns Hopkins University; Li Shi, Medimmune
11:50 AM Evaluating the Ability of a Biomarker to Improve the Diagnosis of Malaria Infection in Malaria 'Challenge' Trials
Holly Janes, Fred Hutchinson Cancer Research Center
12:15 PM Floor Discussion