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Activity Number: 352 - Clinical Trials: Recent Advances in Design and Inference
Type: Contributed
Date/Time: Tuesday, July 31, 2018 : 10:30 AM to 12:30 PM
Sponsor: Korean International Statistical Society
Abstract #327074
Title: Flexible Stochastic Growth Models and Their Experimental Design
Author(s): Nikolaos Demiris* and Konstantinos Kalogeropoulos and Nikolas Kantas
Companies: Athens University of Economics and Business and London School of Economics and Imperial College London
Keywords: Growth curves; Monte Carlo; Non-linear mixed models; optimal design; Stochastic differential equations
Abstract:

Growth models represent a cornerstone in a number of scientific disciplines like medicine, economics and biology. This work is concerned with flexible stochastic processes appropriate for the description of growth phenomena. Motivated by a real dataset on broiler chickens, we embed a wide class of non-linear mixed models within a general diffusion framework and focus on the issue of experimental design. The developed methodology allows to identify the optimal design in this context using sequential Monte Carlo techniques.


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