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Abstract:
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While psychological, social, and environmental factors contribute significantly to physical activity behavior, it is important to recognize that activity behavior also has a biological basis and that genetic variation could affect individuals' propensity to be physically active or sedentary. The SNPs that have been previously identified to be associated with physical activity did not reach genome-wide significance. However, we want to apply a method which has been applied to cardiovascular disease to create a genetic score based on previously published GWAS results. We hypothesize that combining previously identified SNPs into a genetic score will improve on existing methods for detecting association between genetic information and levels of physical activity.
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