Online Program Home
My Program

Abstract Details

Activity Number: 348
Type: Topic Contributed
Date/Time: Tuesday, August 2, 2016 : 10:30 AM to 12:20 PM
Sponsor: Section on Medical Devices and Diagnostics
Abstract #318864 View Presentation
Title: A Bayesian Adaptive Clinical Trial Design: Diagnostic Accuracy of an Olfactory Diagnostic Test for Traumatic Brain Injury in Combat Soldiers
Author(s): Benjamin Saville*
Companies: Berry Consultants
Keywords: diagnostic test ; brain injury ; Bayesian adaptive ; olfactory ; clinical trial
Abstract:

Doctors in combat zones have the difficult task of identifying soldiers who have suffered severe head trauma and require neuroimaging to assess the extent of injury. MRI scans are not readily available in combat zones; hence there is a need for simple and accurate diagnostic tests for traumatic brain injury (TBI) that can be administered in the combat zone. Many studies suggest a correlation between olfactory abilities (sense of smell) and cognitive function. We discuss a clinical trial design to evaluate the diagnostic accuracy of an olfactory test for soldiers to detect moderate/severe TBI. Bayesian methods are used with an adaptive sample size to efficiently estimate sensitivity and specificity of the diagnostic test.


Authors who are presenting talks have a * after their name.

Back to the full JSM 2016 program

 
 
Copyright © American Statistical Association