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CE_33T | Wed, 8/12/2015, 10:00 AM - 11:45 AM | S-Willow A | |
Modern Dose Escalation Trial Designs for Oncology in East (ADDED FEE) — Professional Development Computer Technology Workshop | |||
ASA , Cytel Inc. | |||
Cytel has developed new, industry-standard tools to design, simulate, and operationally support Phase 1 dose escalation trials to determine maximum-tolerated dose (MTD). In addition to the traditional 3+3 design, East® ESCALATE includes Bayesian adaptive approaches, including the modified toxicity probability interval (mTPI) method, the continual reassessment method (CRM), and the Bayesian logistic regression model (BLRM). We will begin by reviewing the underlying theories, and then apply the optimal statistical methods in the process of designing an actual trial. | |||
Instructor(s): Hrishikesh Kulkarni, Cytel Inc. |
For program information, contact the JSM Registration Department or phone (888) 231-3473.
For Professional Development information, contact the Education Department.
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