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371 ! | Tue, 8/11/2015, 10:30 AM - 12:20 PM | CC-615 | |
Power and Sample Size I — Contributed Papers | |||
Biopharmaceutical Section , Survey Research Methods Section | |||
Chair(s): Hong Tian, Janssen Research and Development | |||
10:35 AM | Robust Bayesian Dose-Finding Design for Phase I/II Clinical Trials — Suyu Liu, MD Anderson Cancer Center ; Valen E. Johnson, Texas A&M University | ||
10:50 AM | Association of Dosimetric Parameters with Toxicities in Breast Brachytherapy Treatment with Multi-Lumen Balloon — Jian Kang, Virginia Commonwealth University | ||
11:05 AM | Using Simulation to Compare Performance of Various Prognostic Propensity Scores, Propensity Scores, and Inverse Probability Treatment Weighting (IPTW) Using Propensity Scores — In-Lu Liu, Kaiser Permanente ; Jiaxiao Shi, Kaiser Permanente Southern California ; Wansu Chen, Kaiser Permanente Southern California | ||
11:20 AM | Challenges and Considerations on Sample Size Estimation in Preclinical Discovery Research: Replace, Reduce, Refine — Catherine Tuglus, Amgen ; Lei Zhou, Amgen | ||
11:35 AM | A Dynamic Alpha Spending (DAS) Function with Informative B-Value for a Stratified Study Design — Das Purkayastha, Novartis ; Jagannath Ghosh, Novartis Pharmaceuticals | ||
11:50 AM | Evaluation of Multiplicity Control Strategies for a New Study with Multiple Endpoints and Two Doses — Hua Guo, Actavis ; Kaifeng Lu | ||
12:05 PM | A Novel Tipping Point Approach — Gregory Levin, FDA ; Thomas Permutt, FDA ; Daniel Rubin, FDA |
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