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505 | Wed, 8/12/2015, 8:30 AM - 10:20 AM | CC-205 | |
Clinical Trial Design IV — Contributed Papers | |||
Biopharmaceutical Section , Mental Health Statistics Section | |||
Chair(s): Lyrica Liu, Amgen | |||
8:35 AM | Allele-Specific RNA Expression Modeling Using Finite Mixture Models — Rong Lu, The Ohio State University ; Ryan Smith, The Ohio State University ; Michal Seweryn, The Ohio State University ; Danxin Wang, The Ohio State University ; Amy Webb, The Ohio State University ; Wolfgang Sadee, The Ohio State University ; Grzegorz Rempala, The Ohio State University | ||
8:50 AM | A More Powerful Method to Analyze Bioequivalence for Endogenous Substances in a Crossover Design — Li Fan, Merck ; Lata Maganti, Merck ; Lori A. Mixson, Merck ; Devan Mehrotra, Merck | ||
9:05 AM | Incorporating Historical Data in Bayesian Phase I Trial Design: Evaluating the Similarity in Dose-Toxicity Relationship Between Subgroups — Kentaro Takeda, Astellas ; Satoshi Morita, Kyoto University Graduate School of Medicine | ||
9:20 AM | On the Similarity of Two Dose-Response Curves — Bo Jin, Pfizer Inc. ; Kerry Barker, Pfizer Inc. | ||
9:35 AM | A Comparison of Confidence/Credible Interval Methods for the Area Under the ROC Curve for Continuous Diagnostic Tests with Small Sample Size — Dai Feng, Merck Research Laboratories ; Giuliana Cortese, University of Padova ; Richard Baumgartner, Merck | ||
9:50 AM | Interim Treatment Selection Using Exact Binomial Distribution in Clinical Trials — Bob Zhong, Johnson & Johnson ; Gordon Lan, Johnson & Johnson ; Surya Mohanty, Johnson & Johnson ; Jose Pinheiro, Johnson & Johnson ; Sudhakar Rao, Janssen R&D ; Kyle Wathen, Johnson & Johnson | ||
10:05 AM | Adjusting for Baseline on the Analysis of Repeated Binary Responses with Missing Data — Honghua Jiang ; Pandurang M. Kulkarni, Eli Lilly and Company ; Craig H. Mallinckrodt, Eli Lilly and Company ; Linda Shurzinske, Eli Lilly and Company ; Geert Molenberghs, Universiteit Hasselt/Katholieke Universiteit Leuven ; Ilya Lipkovich, Quintiles |
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