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636 * | Thu, 8/13/2015, 8:30 AM - 10:20 AM | CC-607 | |
Concepts and Methods of Interim Adaptation with Conditional Power — Topic Contributed Papers | |||
Biopharmaceutical Section | |||
Organizer(s): Alison Pedley, Merck | |||
Chair(s): Alison Pedley, Merck | |||
8:35 AM | Futility Monitoring with Conditional Power: A Rationale for the Choice of Theta Assumption Based on Type II Error Probability — Thomas Dobbins, Merck | ||
8:55 AM | Sample Size Adjustment Based on Promising Interim Results and Its Application in Confirmatory Clinical Trials — Joshua Chen, Sanofi Pasteur | ||
9:15 AM | Changing Course Midstream or Giving Up Entirely: Making Decisions on the Basis of Ongoing Data from Clinical Trials — Janet Wittes, Statistics Collaborative | ||
9:35 AM | Cautions in Interpretation of Conditional Power-Based Interim Action Thresholds — Paul Gallo, Novartis Pharmaceuticals | ||
9:55 AM | Discussant: Keaven Anderson, Merck | ||
10:15 AM | Floor Discussion |
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