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526 * ! | Wed, 8/12/2015, 10:30 AM - 12:20 PM | CC-615 | |
New Challenges in Multiplicity Adjustments — Topic Contributed Papers | |||
Biopharmaceutical Section | |||
Organizer(s): Frank Bretz, Novartis | |||
Chair(s): Dong Xi, Novartis | |||
10:35 AM | Group-Sequential Strategies for Clinical Trials When Comparing Two Interventions Using Multiple Co-Primary Endpoints — Toshimitsu Hamasaki, National Cerebral and Cardiovascular Center ; Koko Asakura, National Cerebral and Cardiovascular Center ; Scott R. Evans, Harvard University | ||
10:55 AM | Visualizing Multiple Objectives in Flexible and Group Sequential Designs — Florian Klinglmueller, Medical University Vienna | ||
11:15 AM | Power and Type-1 Error of Global Versus Local Tests with Special Reference to Closed Testing Procedures for Multiple Endpoints in Clinical Trials — Dror Rom, Prosoft Clinical | ||
11:35 AM | Logical Inference on Efficacy in Subgroups and Their Combinations in Personalized Medicine — Jason Hsu, The Ohio State University | ||
11:55 AM | Thresholding of a Continuous Biomarker Based on a New Concept That Correctly Infers Efficacy in the Target Subgroup — Yi Liu ; Jason Hsu, The Ohio State University ; Szu-Yu Tang, Ventana Medical Systems, Inc. | ||
12:15 PM | Floor Discussion |
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