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232 * ! | Mon, 8/10/2015, 2:00 PM - 3:50 PM | CC-609 | |
Adaptive Multi-Stage Clinical Trials with Unblinded Sample Size Re-Estimation: Overview, Recent Development in Methods, and Their Implementation — Topic Contributed Papers | |||
Biopharmaceutical Section , Biometrics Section | |||
Organizer(s): Yili Pritchett, MedImmune | |||
Chair(s): Yili Pritchett, MedImmune | |||
2:05 PM | Unblinded Sample-Size Reassessment in Time-to-Event Clinical Trials — Dominic Magirr | ||
2:25 PM | Implementation of Sample Size Re-Estimation Designs in Confirmatory Clinical Trials — Eva Miller, InVentiv Health Clinical | ||
2:45 PM | 'Promising Zone' Design Case Studies — Zoran Antonijevic | ||
3:05 PM | Exact Confidence Intervals and Unbiased Point Estimates for Adaptive Multi-Stage Clinical Trials — Cyrus Mehta, Cytel Inc. ; Ping Gao, The Medicines Company ; Lingyun Liu, Cytel Inc. | ||
3:25 PM | Floor Discussion |
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