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Activity Number: 499
Type: Contributed
Date/Time: Wednesday, August 12, 2015 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract #317441
Title: Joint Dynamic Modeling of Recurrent Competing Risks and a Terminal Event
Author(s): Piaomu Liu* and Edsel Pena
Companies: University of South Carolina and University of South Carolina
Keywords: Semiparametric ; Dynamic Modeling ; Joint Modeling ; Competing Risks ; Terminal Event
Abstract:

Recurrent events and terminal events occur in many areas in the biomedical and public health settings. In this talk a joint model for recurrent competing risks and a terminal event will be described. Associations among the recurrent competing risks are induced by both a frailty variable and the impact of previous recurrent event occurrences. The recurrent competing risks also impact the occurrence of the terminal event. In addition, further association between the terminal event and the recurrent competing risks is induced by a frailty variable. To dynamically model the impact of interventions after each event occurrence on the recurrent competing risks, an effective age process is introduced. The impact of the increasing number of recurrent event occurrences and covariate processes are also incorporated into the semiparametric model. Estimators of the parameters of the proposed model will be described. Some finite-sample and large-sample properties of estimators will be presented. Issues of prediction of the time to the terminal event for a new observational unit will also be addressed.


Authors who are presenting talks have a * after their name.

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