Abstract Details
Activity Number:
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69
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Type:
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Topic Contributed
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Date/Time:
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Sunday, August 4, 2013 : 4:00 PM to 5:50 PM
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Sponsor:
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Biopharmaceutical Section
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Abstract - #308140 |
Title:
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The Role of Pragmatic Trials in Comparative Effectiveness Research
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Author(s):
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Lehana Thabane*+ and Janusz Kaczorowski and Lisa Dolovich and Larry Chambers and On behalf of the CHAP Investigators
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Companies:
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St Joseph's Healthcare Hamilton and Universite de Montreal and McMaster University and University of Ottawa and McMaster University
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Keywords:
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pragmatic trials; comparative effectiveness research; real world setting
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Abstract:
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Pragmatic trials play a major role in assessing the effectiveness of interventions in the real world. They address a fundmental question of whether offering an intervention, therapy or drug versus some control--which could be usual care or standard of care--does more good than harm in some defined population or setting. Unfortunately, there are many criticims and controversies about pragmatic trials. This presentation will address these confusions and use the CHAP trial (BMJ 2011;342:d442) to illustrate how to deal with the issues.
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Authors who are presenting talks have a * after their name.
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