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Abstract Details
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Activity Number:
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641
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 2, 2012 : 10:30 AM to 12:20 PM
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Sponsor:
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Biometrics Section
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| Abstract - #305396 |
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Title:
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Double Cross-Validation for the Combination of Information in Proteomic Cancer Diagnostic Studies
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Author(s):
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Bart Mertens*+
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Companies:
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Leiden University
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Address:
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LUMC, Gebouw 2, S5-P, Leiden, , Netherlands
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Keywords:
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proteomics ;
prognosis ;
double cross-validation
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Abstract:
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We consider a proteomic mass spectrometry case-control study measuring the proteomic expression of patients and healthy controls. For each patient or control, a pair of two distinct mass spectra is measured, each of which derives from a distinct prior fractionation of the available serum. We use a double cross-validatory procedure for the calibration of a combination predictor on the two distinct spectral sources.
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Authors who are presenting talks have a * after their name.
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