The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.
Abstract Details
Activity Number:
|
518
|
Type:
|
Contributed
|
Date/Time:
|
Wednesday, August 3, 2011 : 10:30 AM to 12:20 PM
|
Sponsor:
|
ENAR
|
Abstract - #303288 |
Title:
|
Change Point Detection In Fmri Functional Connectivity Networks
|
Author(s):
|
Lucy Robinson*+ and Lauren Atlas and Carey Priebe
|
Companies:
|
The Johns Hopkins University and Columbia University and The Johns Hopkins University
|
Address:
|
3400 n charles st, Baltimore, MD, 21218,
|
Keywords:
|
fMRI ;
networks ;
change point ;
neuroscience
|
Abstract:
|
We propose a new technique for detecting time-dependent structure in networks of brain regions. Functional connectivity networks are derived from fMRI data, using partial coherence to describe the degree of connection between spatially disjoint locations in the brain. Existing techniques for functional connectivity networks typically assume the network is static over time. Our goal is to determine whether brain network topology remains stationary, or if subsets of the network exhibit changes over unknown time intervals. Changes in network structure may be related to shifts in neurological state, such as those associated with learning, drug uptake or experimental stimulus. Our approach can detect localized changes, allowing us to infer which nodes in a network exhibit altered connectivity behavior. Using spectral clustering, we define a time-dependent block structure and a test for temporal homogeneity based on a modified likelihood ratio. Data from an experiment studying mediation of pain response by expectancy of relief are analyzed.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2011 program
|
2011 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.