The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.
Abstract Details
Activity Number:
|
220
|
Type:
|
Topic Contributed
|
Date/Time:
|
Monday, August 1, 2011 : 2:00 PM to 3:50 PM
|
Sponsor:
|
Section on Statistical Consulting
|
Abstract - #302509 |
Title:
|
Statistical Pharmacogenomics Studies in Data Services CRO and Biotech
|
Author(s):
|
Kit Lau*+
|
Companies:
|
i3 Statprobe
|
Address:
|
39120 Argonaut Way #568, Fremont, CA, 94538,
|
Keywords:
|
consulting ;
service ;
pharmacogenomics ;
CRO ;
biotech
|
Abstract:
|
Pharmacogenomics (PGx) studies to elucidate biomarkers to predict therapy response and safety are becoming an integral part of clinical trials. The potential of having genomic biomarkers to help tailor therapies for individuals and to predict prognosis is being realized. However, significant challenges in study design and statistical analyses in genomic data remain important road blocks to the success in the field. Statistical learning, data mining methods together with classical statistical techniques to analyze genomic data for clinical utilities would be illustrated, using examples of genetic and genomic studies to elucidate genetic association with drug response and prognostic signature in Neurosciences and Oncology. Through these examples, triumphs and tribulations of working as a CRO statistician in a strategic alliance with big pharmaceutical companies would also be discussed.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2011 program
|
2011 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.