JSM 2011 Online Program

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Abstract Details

Activity Number: 188
Type: Contributed
Date/Time: Monday, August 1, 2011 : 10:30 AM to 12:20 PM
Sponsor: ENAR
Abstract - #301107
Title: Publication Bias in Meta-Analysis
Author(s): Min Chen*+
Companies: ExxonMobil Biomedical Sciences, Inc.
Address: , , ,
Keywords: Meta Analysis ; Publication Bias ; Observational studies ; funnel plot ; Trim and Fill ; Cumulative meta-analysis
Abstract:

Meta-analysis is the statistical synthesis of results of several studies that address a set of related research hypotheses. The synthesis will be meaningful only if the studies have been obtained systematically. However, publication bias is an issue for meta-analysis. Studies with significant results are more likely to be published than those with non-significant results, and published studies are more likely to be included in a meta-analysis than unpublished studies. In this presentation I will address publication bias in meta-analysis for observational studies using various statistical methods including the funnel plot, Rosenthal's Fail-safe, Orwin's Fail-safe N, Duval and Tweedie's Trim and Fill, and the cumulative meta-analysis.


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