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Abstract Details
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Activity Number:
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424
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Type:
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Contributed
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Date/Time:
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Tuesday, August 2, 2011 : 2:00 PM to 3:50 PM
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Sponsor:
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Section on Bayesian Statistical Science
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| Abstract - #300637 |
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Title:
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Sample Size Determination for Drug Combination in Fixed Dose Trials
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Author(s):
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Jie Wang*+
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Companies:
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Quintiles Inc.
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Address:
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6700 W 115th Street, Overland Park, KS, 66211,
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Keywords:
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sample size estimation ;
Bayesian ;
drug combination
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Abstract:
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We have considered the problem of drug combination in fixed dose trials to test whether a drug mixture, which may combine two or more agents, is more 'effective' than each of its components. Informative priors are derived for component drugs and a non-informative prior is assumed for the drug mixture. Sample sizes are evaluated by posterior standard errors, average probability of more effectiveness and Bayesian power.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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