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Abstract Details
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Activity Number:
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640
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Type:
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Invited
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Date/Time:
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Thursday, August 4, 2011 : 10:30 AM to 12:20 PM
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Sponsor:
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ENAR
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| Abstract - #300501 |
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Title:
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Rare Variants and Searching for Associations
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Author(s):
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Joshua Sampson*+ and Hongyu Zhao and John Ferguson
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Companies:
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National Cancer Institute and Yale University and Yale University
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Address:
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Executive Plaza South, Room 8038, Bethesda, MD, 20892,
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Keywords:
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rare variants ;
multivariate test
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Abstract:
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The standard association test examines whether a specific SNP is associated with a disease. However, the genetics community now wants to combine information across multiple SNPs within a gene and determine whether that gene is associated with the disease. Our first goal is to provide a unifying framework for all of the suggested tests. Our second goal is to leverage the common framework of these tests to find an `optimal' or robust test.
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