JSM 2011 Online Program

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Abstract Details

Activity Number: 641
Type: Invited
Date/Time: Thursday, August 4, 2011 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract - #300239
Title: Multiple Imputations in Noninferiority: An Example
Author(s): Rafe Donahue*+
Companies: Biomimetic Therapeutics, Inc.
Address: 389 Nichol Mill Lane, Franklin, TN, 37067,
Keywords: Multiple Imputation ; Non-inferiority
Abstract:

We examine the impact of missing data on analysis of a binary endpoint when the hypothesis of interest is non-inferiority. In particular, we will examine the difference in inference when one assumes missing data as failures versus examining the data using multiple imputations to account for the missing data points.


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