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Abstract Details
Activity Number:
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275
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Type:
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Invited
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Date/Time:
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Tuesday, August 2, 2011 : 8:30 AM to 10:20 AM
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Sponsor:
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ENAR
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Abstract - #300211 |
Title:
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Genetic Association Studies Using Individual and Pooled Sequence Data
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Author(s):
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Hongyu Zhao*+ and Joon Sang Lee
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Companies:
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Yale University and Yale University
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Address:
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300 George Street, New Haven, CT, ,
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Keywords:
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sequencing ;
rare variants ;
pooling ;
association ;
complex traits ;
statistical genomics
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Abstract:
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Second generation sequencing technologies have great promises to identify and associated novel DNA variants with complex diseases. Because the data are extremely information rich yet still expensive to collect, the design and analysis of such data presents many statistical challenges. In this talk, we will discuss several issues encountered in our ongoing studies and describe how statistical principles can be applied to improve design efficiency and derive more robust and efficient statistical tests.
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Authors who are presenting talks have a * after their name.
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