This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Activity Details

670 * Thu, 8/5/2010, 10:30 AM - 12:20 PM CC-111 (West)
Evaluation of Methodology Using Simulations — Contributed Papers
Biopharmaceutical Section
Chair(s): Peiling Yang, FDA
10:35 AM Reducing Parameter Estimation Bias for Data with Missing Values Using Simulation Extrapolation — YU-YI Hsu, Iowa State University ; Yongming Qu, Eli Lilly and Company ; Alicia Carriquiry, Iowa State University
10:50 AM CTDesignExplorer: An Action Queue--Based Open-Source Simulation Experiment Platform for Evaluating Clinical Trial Designs — Yuanyuan Wang, University of Pittsburgh ; Roger Day, University of Pittsburgh ; Daniel Normolle, University of Pittsburgh
11:05 AM A Simulation Study to Compare Modeling Approaches for Dose Proportionality Data — Andrea Maes, Novartis Pharmaceuticals Corporation ; Wen-Lin Luo, Merck & Co., Inc. ; Yu Ding, Merck Research Laboratories ; Deborah Panebianco, Merck & Co., Inc.
11:20 AM A Simulation Study to Evaluate Sample Size and Power for a Trial to Develop a Prediction Rule Using Machine Learning Methods — Radha Railkar, Merck & Co., Inc. ; Matthew Wiener, Merck & Co., Inc. ; Leonidas Carayannopoulos, Merck & Co., Inc.
11:35 AM Impact of Missing Data on Type 1 Error Rates in Noninferiority Trials — Bongin Yoo, Bristol-Myers Squibb
11:50 AM Point and Interval Estimations for Difference of Two Proportions in Incomplete Matched-Paired Data Using Expectation-Maximization Algorithm — Adeniyi J. Adewale, Merck & Co., Inc. ; Benjamin B. John, EdgeServe LLC
12:05 PM Estimation of Confidence Intervals for the Log-Normal Mean — Lingmin Zeng, MedImmune ; Lanju Zhang, MedImmune ; Harry Yang, MedImmune



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