This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
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658
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 5, 2010 : 10:30 AM to 12:20 PM
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Sponsor:
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IMS
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Abstract - #309505 |
Title:
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Two Sample Mann-Whitney Test with Adjustments to Pre-treatment Variables
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Author(s):
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Chengyong Tang*+ and Song X. Chen and Jing Qin
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Companies:
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National University of Singapore and Iowa State University/Peking University and National Institute of Allergy and Infectious Diseases
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Address:
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6 Science Drive 2, Singapore , 117546, Singapore
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Keywords:
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Abstract:
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The conventional Wilcoxon/Mann-Whitney tests may be invalid due to the presence of certain pre-treatment variables which contribute to the propensity of the missingness or the allocation of treatments in observational studies. We propose an adjusted Mann-Whitney test for comparison of treatment effects between two samples that is applicable for both missing outcomes and observational studies. We also propose a semiparametrically adjusted Mann-Whitney test which leads to dimension reduction for high dimensional covariate when a parametric propensity model for the missingness or the treatment allocation is available. A novel bootstrap procedure is devised to approximate the null distribution of the test.
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