This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
|
312
|
Type:
|
Contributed
|
Date/Time:
|
Tuesday, August 3, 2010 : 8:30 AM to 10:20 AM
|
Sponsor:
|
Section on Statistics in Epidemiology
|
Abstract - #309141 |
Title:
|
Plausible 'Nuisance' Contributor to Decreasing Deleterious Association of Overweight and Obese on Mortality Rate Over Calendar Time
|
Author(s):
|
Tapan Mehta* and Nicholas Pajewski and Scott Keith and Kevin Fontaine and David B. Allison+
|
Companies:
|
The University of Alabama at Birmingham and The University of Alabama at Birmingham and Thomas Jefferson University and The Johns Hopkins University School of Medicine and The University of Alabama at Birmingham
|
Address:
|
1665 University Blvd. , Birmingham, AL, 35294-002,
|
Keywords:
|
BMI - Body Mass Nndex ;
NHANES -National Health and Nutrition Examination Surveys ;
HR - hazard ratio ;
MR - mortality rate
|
Abstract:
|
NHANES analyses have suggested that the harmful effects of obesity may have decreased over calendar time. We hypothesized that statistical artifact introduced by the influence of a shifting BMI distribution and the application of fixed BMI categories on the association of obesity with MR may partly or entirely explain the reduction. NHANES I with linked mortality were used to optimally fit a Cox model with BMI as a continuous predictor in presence of covariates to derive a 'true' model. Coefficients estimated from the 'true' model were used to simulate mortality for NHANES III. Hence null was set such that BMI-MR relation in NHANES I and III is same. Then in NHANES I and III HRs were computed for 5 BMI categories. We tested whether the HR estimates for BMI categories between NHANES I and III were equal. Results indicated that some of the apparent BMI-MR reduction is due to the artifact.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.