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Abstract Details

Activity Number: 553
Type: Invited
Date/Time: Wednesday, August 4, 2010 : 2:00 PM to 3:50 PM
Sponsor: Section on Nonparametric Statistics
Abstract - #308944
Title: Bayesian Clustering for Failure-Time Data
Author(s): Gary Rosner*+ and Peter Mueller and Fernando Quintana
Companies: The Johns Hopkins University and MD Anderson Cancer Center and Pontificia Universidad Católica de Chile
Address: 550 N. Broadway, Baltimore, MD, 21205, United States
Keywords: Bayesian nonparametric methods ; Product partition models ; Survival analysis
Abstract:

We discuss a model-based clustering algorithm that exploits available covariates. The motivating application concerns predicting event-free survival of patients in a breast cancer trial. We build on product partition models (PPM) by defining an extension of the PPM to include a regression on covariates. The cohesion function in the PPM includes a new factor that increases the probability that experimental units with similar covariates will be included in the same cluster. Posterior predictive inference in this model formalizes the desired prediction.


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