This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
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259
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Type:
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Contributed
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Date/Time:
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Monday, August 2, 2010 : 2:00 PM to 3:50 PM
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Sponsor:
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Health Policy Statistics Section
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Abstract - #308402 |
Title:
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Simulation of Kidney Paired Donation Programs
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Author(s):
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Yijiang (John) Li*+ and Yan Zhou and John David Kalbfleisch and Peter Song
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Companies:
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University of Michigan and University of Michigan and University of Michigan and University of Michigan
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Address:
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Department of Biostatistics, Ann Arbor, MI, 48105,
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Keywords:
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Kidney Paired Donation ;
Simulation Models ;
Optimal Exchange ;
Expected Utility ;
Integer Programming
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Abstract:
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Kidney paired donation (KPD) programs provide an important platform for living incompatible donor/recipient pairs to exchange organs to achieve mutual benefit. Our innovative simulation utilizes empirically based models of donor and recipient characteristics and arrival patterns to a KPD program and explicitly takes into consideration outcome based and rule based utilities (e.g. allograft survival or life years gained from transplant); in addition, it models probabilities that a chosen exchange will actually be implemented. We develop a new strategy that is able to exploit possible alternative transplants that might be performed when a planned exchange fails. Optimal exchanges can be obtained using integer programming techniques and simulation models allow tracking of the KPD over a series of match runs to evaluate various utilities and strategies. Some example simulations are given.
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Authors who are presenting talks have a * after their name.
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