This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
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513
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Type:
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Contributed
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Date/Time:
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Wednesday, August 4, 2010 : 10:30 AM to 12:20 PM
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Sponsor:
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Biopharmaceutical Section
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Abstract - #307788 |
Title:
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Who Should I Vaccinate? Let Me Look Into My CART
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Author(s):
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Oliver Bautista*+
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Companies:
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Merck & Co., Inc.
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Address:
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P.O. Box 1000, UG1CD-44, North Wales, PA, 19454-2505, USA
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Keywords:
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CART ;
tree-based methods ;
prophylactic vaccination
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Abstract:
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GARDASIL is a prophylactic vaccine that is efficacious in preventing cervical and external genital disease related to the vaccine-HPV types (6,11,16,18) among young women who are naïve to the vaccine-HPV types. The older women population who have longer life-time exposure to HPV is expected to have a larger proportion of vaccine-HPV type non-naïve women for whom the vaccine will not be as efficacious compared to younger women. A cost-free method for predicting if an older woman is highly likely to be vaccine-HPV type naïve that excludes a polymerase chain reaction (PCR) test, the definitive method of detecting HPV infection, is a desirable tool for identifying older women likely to benefit from vaccination with GARDASIL. Results of investigations to identify such a method using classification and regression trees (CART) are presented.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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