This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
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253
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Type:
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Contributed
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Date/Time:
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Monday, August 2, 2010 : 2:00 PM to 3:50 PM
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Sponsor:
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Section on Statistics in Epidemiology
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Abstract - #307477 |
Title:
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Optimal Stratification of a Continuous Variable Using Overall C-Index and ROC
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Author(s):
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Sunita Ghosh*+
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Companies:
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Alberta Health Services
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Address:
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11560 University ave., Edmonton, AB, T6G 1Z2, Canada
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Keywords:
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optimal stratification ;
overall c-index ;
ROC ;
cross-validation ;
jackknife
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Abstract:
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Studies in clinical or epidemiological setting usually involve categorization of a continuous variable. Several methods have been proposed in literature to determine the optimal cut-point of a continuous variable. In the present paper we will be using overall c-index and receiver operating curve (ROC) to determine the optimal cut-point, and will be comparing both these methods and test for the most unbiased optimal cut-point. Two-fold cross-validation and Jackknife methods will be used to validate the cut-point methods. The cut-point will be determined based on univariable as well as multivariable setting. The cut-point will be determined for binary as well as survival outcome.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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