This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
|
117
|
Type:
|
Topic Contributed
|
Date/Time:
|
Monday, August 2, 2010 : 8:30 AM to 10:20 AM
|
Sponsor:
|
Biopharmaceutical Section
|
Abstract - #306900 |
Title:
|
Multinational Clinical Trials: A Perspective from Latin America
|
Author(s):
|
Carolina Cernadas*+
|
Companies:
|
Schering Plough Argentina
|
Address:
|
, , , Argentina
|
Keywords:
|
Multinational trials ;
power ;
variance ;
latin america
|
Abstract:
|
An increasing number of multinational trials to support marketing approval in the US have been implemented. One important issue is the unexpected sources of variability. Factors such as local demographics, ethnicity, medical practices and investigators training, may differ among the regions and impact the final outcomes. These factors often present statistical challenges and lead to nuisance qualitative interactions amoung different regions. Having more accurate definitions of regions and a better understanding of relevant variables such as demographic, cultural and economical factors in the design stage is important to minimize nuisance variability, properly power the trial and to obtain meaningful and relevant results. The Latin American region will be used as an example.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.