This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
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Activity Number:
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123
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Type:
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Topic Contributed
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Date/Time:
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Monday, August 2, 2010 : 8:30 AM to 10:20 AM
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Sponsor:
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Section on Nonparametric Statistics
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| Abstract - #306755 |
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Title:
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Odds Ratio Bias in Case-Control Studies Using Robust Genetic Models
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Author(s):
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Neal Jeffries*+
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Companies:
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National Heart, Lung, and Blood Institute
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Address:
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6701 Rockledge Dr., MSC 7913, Bethesda, MD, 20892,
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Keywords:
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robust genetic models ;
winner's curse ;
ranking bias ;
significance bias
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Abstract:
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We explore the degree of selection bias arising from robust genetic procedures that first assess the genetic model and then estimate an odds ratio associated with that model. Bias in the odds ratio can arise from both the method of selection as well as requiring a statistically significant degree of association. The degree of bias is assessed for a particular robust genetic model procedure, MAX3, and some methods for detection and correction of bias are presented.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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