This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
|
57
|
Type:
|
Topic Contributed
|
Date/Time:
|
Sunday, August 1, 2010 : 4:00 PM to 5:50 PM
|
Sponsor:
|
Biopharmaceutical Section
|
Abstract - #306573 |
Title:
|
A Projection of True-early-detection, No-early-detection, Overdiagnosis and Not-so-necessary Probabilities in Tumor Screening
|
Author(s):
|
Dongfeng Wu*+ and Gary L. Rosner
|
Companies:
|
University of Louisville and MD Anderson Cancer Center
|
Address:
|
485 E. Gray Street, Louisville, KY, 40202,
|
Keywords:
|
cancer screening ;
true-early-detection ;
no-early-detection ;
over-diagnosis ;
sensitivity ;
sojourn time
|
Abstract:
|
A probability model for evaluating long-term effects due to periodic screening was developed. Peoples who take part in cancer screening were categorized into 4 disjoint groups: True-early-detection, No-early-detection, Overdiagnosis and Not-so-necessary. The probability of each case was derived. Simulation studies using the HIP breast cancer study data provide estimates for these probabilities and corresponding credible intervals. These probabilities change with a person's age at study entry, screening frequency, sensitivity, and other parameters. We also allow human lifetime to be subject to a competing risk of death from other causes. The model can provide policy makers crucial information regarding the distribution of participants in a screening program who fall into one of the 4 categories. The method is applicable to other kinds of screening as well.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.