This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
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343
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Type:
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Contributed
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Date/Time:
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Tuesday, August 3, 2010 : 10:30 AM to 12:20 PM
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Sponsor:
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ENAR
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Abstract - #306392 |
Title:
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A Bivariate Mover-Stayer Model for Interval-Censored Recurrent Event Data: Application to Joint Damage in Rheumatology
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Author(s):
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Rinku Sutradhar*+
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Companies:
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Institute for Clinical Evaluative Sciences
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Address:
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G Wing - 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
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Keywords:
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Heterogeneity ;
Association ;
Inetrval censoring ;
Joint damage ;
Non-susceptible fraction
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Abstract:
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Interval-censored recurrent event data can exhibit considerable between subject heterogeneity in the event rate, and frequently there is a proportion of individuals experiencing no events. We consider a likelihood based analysis of bivariate interval-censored recurrent event data in which a random effect is used to accommodate heterogeneity in the rate of events, and bivariate mover-stayer indicators are introduced to accommodate a nonsusceptible sub-population for each type of event. The motivating data arises from a study on joint damage in patients with psoriatic arthritis. For every patient, each joint is assessed for damage using both clinical and radiological measures over the duration of follow-up. The proposed model facilitates estimation of the joint distribution of the mover-stayer indicators for both clinical and radiological joint damage.
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