This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
|
212
|
Type:
|
Invited
|
Date/Time:
|
Monday, August 2, 2010 : 2:00 PM to 3:50 PM
|
Sponsor:
|
WNAR
|
Abstract - #305986 |
Title:
|
Estimating Optimal Dynamic Treatment Regimes with Shared Decision Rules Across Stages: An Extension of Q-learning
|
Author(s):
|
Bibhas Chakraborty*+ and Erica E.M. Moodie
|
Companies:
|
Columbia University and McGill University
|
Address:
|
, , ,
|
Keywords:
|
dynamic treatment regime ;
non-regularity ;
soft-threshold ;
shared ;
bootstrap
|
Abstract:
|
Dynamic treatment regimes (DTR) offer a framework to operationalize the adaptive multistage decision making in clinical practice. Formally, a DTR is a set of decision rules, one per stage; each decision rule takes a patient's treatment and covariate history as input, and outputs a recommended treatment. In some studies, these decision rules are shared across stages of treatment, i.e. the decision rule at each stage is the same function of the history available at that stage. Because of this sharing phenomenon, recursive methods like Q-learning that move backward through stages are not suitable; simultaneous estimation techniques are necessary. In this paper, we propose a simultaneous estimation procedure for the optimal DTR with shared decision rules, adjusting for non-regularity via thresholding. We compare the performance of the proposed method to other approaches through simulation.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.