JSM Preliminary Online Program
This is the preliminary program for the 2009 Joint Statistical Meetings in Washington, DC.

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Activity Number: 362
Type: Topic Contributed
Date/Time: Tuesday, August 4, 2009 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #305671
Title: Supplementing a Validation Test Sample
Author(s): Frank W. Samuelson*+
Companies: FDA
Address: 10903 New Hampshire Ave, Silver Spring, MD, 20993-0002,
Keywords: learning machines ; test ; validation ; supplement
Abstract:

Requiring an independent, external test sample is standard for obtaining unbiased performance validation of diagnostic learning machines. Learning machines evolve over time as developers improve their performance and repeated validation of these learning machines may be necessary. Repeated use of a fixed validation test sample will lead to bias and optimistic estimates, but obtaining an entirely new test sample with every validation may not be possible. This presentation suggests a method for supplementing a test sample with additional cases such that the performance of the learning machine on repeated use of that test sample must have limited bias, given certain assumptions. This limit is used to construct a criterion for the size of a supplement for a test sample that is modest and depends only upon the size of the original test sample.


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