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Activity Number:
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134
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Type:
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Contributed
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Date/Time:
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Monday, August 3, 2009 : 8:30 AM to 10:20 AM
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Sponsor:
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International Chinese Statistical Association
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| Abstract - #305074 |
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Title:
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Comparison of Different Statistical Analysis Strategy on Evaluating Drug Eluting Stent Trial
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Author(s):
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Wei Li and Yang Wang*+
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Companies:
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Peking Union Medical College and National Center for Cardiovascular Diseases
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Address:
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167 Bei Li Shi Lu, Beijing, 100037, China
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Keywords:
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Statistical Analysis Strategy ; Drug Eluting Stent Trial ; Multilesion
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Abstract:
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The number of multi-lesion catheter interventions has increased markedly during the past few years. This raises the issue of how to methodologically address multi-lesion patients in studies searching for predictive factors of restenosis. Analyzing data on a patient-specific basis by selecting the worse (tighter) stenosis, random selection of only 1 lesion per patient and average the response of all lesions in 1 patient were the acceptable strategy. All the strategy has a common disadvantage they can not fully use the data information. As compare, a lesion-based analysis would make full use of the data but the problem is the potential correlation of restenosis between the lesions of the same patient. We will compare the above mentioned strategy uses a real world 8000 patients database, to see the same and difference between each method.
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