JSM Preliminary Online Program
This is the preliminary program for the 2009 Joint Statistical Meetings in Washington, DC.

The views expressed here are those of the individual authors
and not necessarily those of the ASA or its board, officers, or staff.

Back to main JSM 2009 Program page

Activity Number: 219
Type: Contributed
Date/Time: Monday, August 3, 2009 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistical Computing
Abstract - #303729
Title: Case Studies of Power Analysis for Clinical Trial Designs by Using Simulations
Author(s): Junxiang Luo*+
Companies: Eli Lilly and Company
Address: , , 46285,
Keywords: simulation ; power analysis ; sample size ; negative binomial ; frailty model ; bootstrap
Abstract:

To illustrate statistical power analysis by using simulation to estimate sample size in clinical trial designs, three cases are presented in the paper. The first two cases are for negative binomial regression on count data with over dispersion, and for time to event responses based on a frailty model with random effect, respectively. In the third example, simulation is applied to estimating sample size for a non-inferiority hypothesis test to compare percentiles between two groups. The confidence interval of difference of percentiles is estimated by bootstrap methodology.

  • The address information is for the authors that have a + after their name.
  • Authors who are presenting talks have a * after their name.

Back to the full JSM 2009 program


JSM 2009 For information, contact jsm@amstat.org or phone (888) 231-3473. If you have questions about the Continuing Education program, please contact the Education Department.
Revised September, 2008