JSM Preliminary Online Program
This is the preliminary program for the 2007 Joint Statistical Meetings in Salt Lake City, Utah.

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Activity Number: 201
Type: Contributed
Date/Time: Monday, July 30, 2007 : 2:00 PM to 3:50 PM
Sponsor: ENAR
Abstract - #310135
Title: Imaging Biomarkers and Sample Size Estimation
Author(s): Chunming Li*+
Companies: Pfizer Inc.
Address: 2 Continental Court, South River, NJ, 08882,
Keywords: magnetic resonance imaging ; measurement error ; log-normal ; effect size ; maximum likelihood
Abstract:

In the presentation, I will begin with a brief discussion of some common medical imaging modalities in clinical studies. I will elaborate on several study objectives using imaging biomarkers. However, the main focus will be on an imaging biomarker application and related study design and statistical methodology. I will discuss the statistical modeling, associated power calculation and simulation results. In the end, I will share some of the challenging issues in imaging clinical trials.

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Revised September, 2007