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Activity Number: 94
Type: Topic Contributed
Date/Time: Monday, July 30, 2007 : 8:30 AM to 10:20 AM
Sponsor: Biopharmaceutical Section
Abstract - #309596
Title: A Simulation Study on Covariate Adjusted Models
Author(s): Xiaohong Huang*+ and Abdul Sankoh
Companies: sanofi-aventis and sanofi-aventis
Address: 200 Crossing Blvd, Bridgewater, NJ, 08807,
Keywords: covariate adjusted ; power
Abstract:

Covariate adjusted analysis aims to adjust the treatment difference by taking into account of the unbalanced underlying characteristic between treatment groups. Simulation studies were performed to examine the effect of covariate adjustment. Power and alpha level will be compared between unadjusted and adjusted models.


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Revised September, 2007