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This is the preliminary program for the 2007 Joint Statistical Meetings in Salt Lake City, Utah.

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Activity Number: 323
Type: Topic Contributed
Date/Time: Tuesday, July 31, 2007 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #309194
Title: On the Use of Fisher's Exact Test When Randomization Is Sitewise
Author(s): Shanti Gomatam*+
Companies: Food and Drug Administration
Address: 1350 Piccard Dr HFZ 550, Rockville, MD, 20850,
Keywords: center-specific randomization ; clinical trials ; Exact test
Abstract:

Fisher's exact test is often used in the analysis of data from clinical trials. However, whereas Fisher's exact test assumes overall randomization, randomization implementation in most trials is center-specific. Does this make a difference? This question is addressed here.

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Revised September, 2007