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Activity Number: 494
Type: Topic Contributed
Date/Time: Thursday, August 2, 2007 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #309093
Title: Dynamic Positron Emission Tomography Data-Driven Analysis Using Sparse Bayesian Learning
Author(s): John Aston*+ and Jyh-Ying Peng
Companies: Academia Sinica and Academia Sinica
Address: Institute of Statistical Science, Taipei, 115, Taiwan
Keywords: Sparse Bayesian Learning ; PET ; Exponential Bases
Abstract:

A method is presented for the analysis of dynamic PET data using sparse Bayesian learning. Parameters are estimated in a compartmental framework using an over-complete exponential basis set and sparse Bayesian Learning. The technique is applicable to analyses requiring either a plasma or reference tissue input function and produces estimates of the system's macro-parameters and model order. The method is applied to the estimation of parametric images of neuroreceptor radioligand studies.


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Revised September, 2007